Hot pizza vs leftover cold pizza? This article lays out this question and provides some science-ish support.
"Scientists speculate on why this group prefers chilled pizza. Chilling foods mellows the flavors, particularly those that are bitter or sweet. Meanwhile, the taste receptors for saltiness are stronger in cold temperatures. This mutes the sweetness of the tomato sauce, causing the pizza to taste saltier. Other, more delicate flavors, such as the herbs in the sauce, can also come through stronger."
While the melding of flavors is important, however I think there are factors that are more important. First, we must recognize that not all pizza is the same, and there are big differences on which will be better cold or better reheated.
The dough is a major factor. A very thick dough can be overly chewy when cold and is better on reheating. And if that thick dough was overly doughy initially, reheating it can make it better than it was initially.
As for cheese, it depends on the type of cheese. Some cheeses are better hot, while some may be better cold. I am not the cheese expert (our cheese expert retired), but as a pizza aficionado (grew up in NE PA, pizza capital of the world, and worked for a real pizza shop (not one of these cookie-cutter chains) for 4 years (age 15-18)), I have seen some pizza cheese turn from excellent hot to nothing more than rubber when cold. This is not only a textural issues, but flavors as well.
The beverage served as a lot to do with this as well. You can pair hot pizza with beer or wine, but with cold pizza, I just don't see it. I like my cold pizza with milk.
So do you have a favorite pizza joint and is that pizza good when cold?
Morning Clips
https://www.morningagclips.com/does-cold-pizza-actually-taste-better-the-science-of-leftovers/
Does Cold Pizza Actually Taste Better? The Science of Leftovers
Leftover pizza may be best served cold, but most other leftovers require reheating
PUBLISHED ON September 24, 2025
WASHINGTON — The best way to eat pizza is an ongoing debate. In Pizza Hut’s second annual Pizza Trends Report, 57% of Americans prefer their leftover pizza cold, and science suggests there might be something to the claim. From the oxidation of food molecules to the role of starch, here’s what happens to leftover food in your fridge and how to make the most of it.